The treatment of newly diagnosed metastatic hormone-sensitive prostate cancer (mHSPC) has evolved in recent years with the approval of hormonal agents such as Zytiga (Johnson & Johnson), Xtandi (Pfizer / Astellas Pharma), and the next-generation androgen receptor inhibitor Erleada (Johnson & Johnson). Although these therapies have improved patient outcomes, substantial unmet need remains for novel therapies with better efficacy and improved safety and tolerability. Therefore, the therapeutic management of newly diagnosed mHSPC presents an enormous commercial opportunity for drug developers.

QUESTIONS ANSWERED

  • What treatment drivers and goals are most likely to influence the choice of therapy for newly diagnosed mHSPC?
  • What attributes are key influencers of prescribing, and what are the hidden opportunities for drug developers?
  • What are the prevailing areas of unmet need and opportunity in this patient population?
  • What trade-offs across different clinical attributes and prices are acceptable to U.S. and European medical oncologists for a hypothetical therapy for newly diagnosed mHSPC?

PRODUCT DESCRIPTION

Unmet Need supports clinical development decisions by identifying key attributes and assessing areas of unmet need for a specific disease or subpopulation. Based on surveys with U.S. and European physicians, this report provides insight into key treatment drivers and goals, the performance of current therapies, and the remaining commercial opportunities. One market scenario is profiled in detail by DRG experts, and additional customized market scenarios can be evaluated with the corresponding TPP simulator.

Markets covered: United States, United Kingdom, France, Germany

Primary research: Survey of 61 U.S. medical oncologists and 30 European medical oncologists

Key drugs: Zytiga, Erleada, Xtandi, Taxotere / docetaxel generics

Table of contents

  • Prostate Cancer - Unmet Need - Detailed, Expanded Analysis - Metastatic Hormone Sensititve

Author(s): Snigdha Gupta, Ph.D

Dr. Snigdha Gupta is a Lead Analyst in the oncology team at Decision Resources Group with expertise in multiple oncology indications including non-small cell lung cancer and multiple myeloma.

Prior to joining DRG, Dr. Snigdha Gupta was a subject matter expert in immune-oncology, autoimmunity and dealt in generating in-depth framework based scientific analyses for client projects. In her previous organizations, she was involved in the planning and execution of the IND enabling preclinical studies. She has been instrumental in the stage-up of two small molecules at Bioxcel Therapeutics and Daiichi Sankyo Pharma India Pvt. Ltd. Dr. Gupta holds Ph.D. in infectious diseases from the Indian Institute of Chemical Biology, Jadavpur University, Kolkata while her post-doctoral fellowship is from the Mucosal immunology labs of National Institute of Immunology, New Delhi.


Related Reports

Prostate Cancer - Landscape & Forecast - Disease Landscape & Forecast

Prostate cancer is the most common cancer among men in developed countries. Hormonal agents are the mainstay of treatment for prostate cancer and are routinely used across lines. Zytiga (...

View Details

Prostate Cancer | Disease Landscape and Forecast | G7 | 2019

Market Outlook Prostate cancer is the most common cancer among men in developed countries. Hormonal agents are the main treatment for prostate cancer and are routinely used...

View Details