The increasing prevalence and severity of Gram-negative infections (GNIs) caused by extended-spectrum beta-lactamase (ESBL)-producing pathogens have emerged as a global public health concern. Recent surveillance studies find that an increasing proportion of ESBL-producing pathogens are also associated with resistance to other classes of antibiotics, further limiting therapeutic options. As such, new antibiotics with activity against ESBL-producing Gram-negative pathogens represent a key unmet need in the GNI therapy market.

Table of contents

  • Hospital-Treated Gram-Negative Infections - Unmet Need - Detailed, Expanded Analysis: Gram-Negative Infections Due To Extended-Spectrum Beta-Lactamase-Producing Pathogens

Author(s): Jiamin Zhuo, PhD

Jiamin Zhuo, Ph.D., is a business insights analyst on the infectious, niche, and rare diseases team at Decision Resources Group. He provides expert insight into the commercial aspects of drug development and market dynamics in bacterial infections, including gram-negative infections and Methicillin-resistant Staphylococcus aureus.

He attained his Ph.D. at the Mayo Graduate School, Mayo Clinic, in Minnesota and his B.Sc. in physiology from Peking University in China. Prior to joining DRG, Dr. Zhuo was a postdoctoral fellow at Boston University and MIT, where he gained extensive experience in quantitative research methods.