Although favorable demographics and the launch of innovative new products will drive continued growth in the US market for skin replacements and substitutes, challenges in the biologic product segment, including reimbursement issues and increased regulatory oversight, will hinder market expansion to some extent.

This Medtech 360 Report provides comprehensive data and analysis on the current state of the market for skin replacements and substitutes in the US across a 10-year period.

Amniotic-derived allografts have experienced rapid adoption in the biologic skin replacement and substitute segment.

Which companies have benefited most from the adoption of these products?

How has this shift in product preference affected the traditional allograft market? 

Will the trend toward increased use of amniotic products continue?

How will increased regulatory oversight of amniotic tissue products affect existing amniotic allografts and the development of new products?

Reimbursement changes in the US have affected payment for skin replacements and substitutes.

What is the current reimbursement system for skin replacements and substitutes?

What are some strategies companies can employ to receive favorable reimbursement?

Product launches, acquisitions, and partnerships represent key competitive strategies in this space.

Which competitors are launching new products and in which segments? 

Which segments will see the most acquisition activity?

How are partnerships and acquisitions helping smaller companies compete with more established competitors?

Clinical data are of utmost importance to physicians when choosing skin replacements and substitutes. 

Why do physicians feel so strongly about clinical data when it comes to skin replacements and substitutes?

Which companies are investing in clinical trials? 

How have results from recent clinical trials affected company performance? 

Table of contents

  • Skin Replacements And Substitutes - Market Insights - United States
    • Abstract
    • Executive Summary
      • COVID-19 Updates
        • Market Highlights
          • Factors Impacting the Skin Replacement and Substitute Market, by Product Type, US
          • Skin Replacement and Substitute Market, by Product Type, US (USD), 2019–2029
          • Skin Replacement and Substitute Market Landscape, US (USD), 2019 and 2029
        • Competitive Highlights
          • Competitive Factors and Strategies, by Product Type, US
          • Skin Replacement and Substitute Revenue Market Share Rankings, by Product Type, US, 2019
          • Companies Mentioned
        • Market Developments
          • Recent Events in the Skin Replacement and Substitute Market, US
          • Emerging Products for the Skin Replacement and Substitute Market, US
        • End-User Insights
          • Procedures Covered
            • Skin Replacement and Substitute Procedures Covered, US
          • Products Covered
            • Skin Replacement and Substitute Products Covered, US
        • Key Report Updates
          • COVID-19 Analysis
            • Market Impact
              • COVID-19 Impact Assessment Summary, Skin Replacement and Substitute Market, US
            • Guidance and Recommendations
              • Guidance and Recommendations for Skin Replacement and Substitute Procedures
            • Industry and Clinician Perspectives
              • Major Market Forecast Changes and Assumptions
                • Skin Replacement and Substitute Market, by Product Type, US (USD), 2019–2029 (Excluding COVID-19 Impact)
                • Skin Replacement and Substitute Market, by Product Type, US (USD), 2019–2029 (Including COVID-19 Impact)
              • Competitive Impact
                • COVID-19 Competitive Factors and Strategies, Skin Replacement and Substitute Market, US
                • COVID-19 Impact by Competitor, Skin Replacement and Substitute Market
            • Skin Replacement and Substitute Market
              • Market Highlights
                • Factors Impacting the Skin Replacement and Substitute Market, by Product Type, US
                • Skin Replacement and Substitute Market, by Product Type, US (USD), 2019–2029
              • Market Definitions
                • Market Forecast Data
                  • Skin Replacement and Substitute Procedures, by Product Type, US, 2019–2029
                  • Skin Replacement and Substitute Market, by Product Type, US (USD), 2019–2029
                  • Skin Replacement and Substitute Market Growth, by Product Type, US, 2020–2029
                • Competitive Highlights
                  • Market Shares
                    • Skin Replacement and Substitute Revenue Market Shares, US, 2019
                    • Skin Replacement and Substitute Revenue Market Shares, by Product Type, US, 2019
                  • Competitive Factors and Strategies
                    • Competitive Factors and Strategies, by Product Type, US
                  • Market Developments
                    • Recent Events in the Skin Replacement and Substitute Market, US
                    • Emerging Products for the Skin Replacement and Substitute Market, US
                • Biologic Skin Replacement and Substitute Market
                  • Market Highlights
                    • Biologic Skin Replacement and Substitute Market, by Material, US (USD), 2019–2029
                  • Market Definitions
                    • Market Forecast Data
                      • Biologic Skin Replacement and Substitute Market, US (USD), 2019–2029
                      • Biologic Skin Replacement and Substitute Market, by Material, US (USD), 2019–2029
                      • Biologic Skin Replacement and Substitute Market Growth, by Material, US, 2020–2029
                      • Allograft Biologic Skin Replacement and Substitute Market, by Origin, US (USD), 2019–2029
                      • Allograft Biologic Skin Replacement and Substitute Market Growth, by Origin, US, 2020–2029
                      • Biologic Skin Replacement and Substitute Market, by Product Type, US (USD), 2019–2029
                      • Biologic Skin Replacement and Substitute Market Growth, by Product Type, US, 2020–2029
                      • Biologic Skin Replacement and Substitute Market, by Product Feature, US (USD), 2019–2029
                      • Biologic Skin Replacement and Substitute Market Growth, by Product Feature, US, 2020–2029
                      • Biologic Skin Replacement and Substitute Market, by Storage Type, US, 2019–2029
                      • Biologic Skin Replacement and Substitute Market Growth, by Storage Type, US, 2020–2029
                    • Competitive Highlights
                      • Market Shares
                        • Biologic Skin Replacement and Substitute Revenue Market Shares, US, 2019
                        • Biologic Skin Replacement and Substitute Revenue Market Shares, US, 2019
                      • Competitive Factors and Strategies
                        • Competitive Factors and Strategies, by Product Type, US
                    • Biosynthetic Skin Replacement and Substitute Market
                      • Market Highlights
                        • Biosynthetic Skin Replacement and Substitute Market, US (USD), 2019–2029
                      • Market Definitions
                        • Market Forecast Data
                          • Biosynthetic Skin Replacement and Substitute Market, US (USD), 2019–2029
                          • Biosynthetic Skin Replacement and Substitute Market, by Product Type, US (USD), 2019–2029
                          • Biosynthetic Skin Replacement and Substitute Market Growth, by Product Type, US, 2020–2029
                          • Biosynthetic Skin Replacement and Substitute Market, by Storage Type, US, 2019–2029
                          • Biosynthetic Skin Replacement and Substitute Market Growth, by Storage Type, US, 2020–2029
                        • Competitive Highlights
                          • Market Shares
                            • Biosynthetic Skin Replacement and Substitute Revenue Market Shares, US, 2019
                            • Biosynthetic Skin Replacement and Substitute Revenue Market Shares, US, 2019
                          • Competitive Factors and Strategies
                            • Competitive Factors and Strategies, US
                        • Appendix
                          • Abbreviations
                            • Bibliography

                          Author(s): Mark O'Reilly, MSc

                          Mark O'Reilly is an analyst on the Orthopedics, Dental, and Aesthetics Medtech Insights team at DRG (Part of Clarivate), focused on the skin replacement and substitute, spinal implant, and large-joint reconstructive implant markets. Mark holds both a Bachelor’s and Master’s degree in Biomedical Engineering from the University of Guelph and Western University, respectively.