LaunchTrends: Tafinlar and Mekinist is a series of three post-launch syndicated reports designed to track physician perception and uptake of newly launched Tafinlar (GlaxoSmithKline’s dabrafenib) and Mekinist (GlaxoSmithKline’s trametinib).
LaunchTrends: Tafinlar and Mekinist measures the impact of these new agents on the unresectable and metastatic melanoma market following launch. The study surveys medical oncologists from the United States and conducts qualitative interviews with physicians. This report evaluates physicians’ current awareness and perception of Tafinlar and Mekinist and Tafinlar and Mekinist combination therapy relative to other currently available therapies for unresectable and metastatic melanoma, current and anticipated usage of Tafinlar, Mekinist, and Tafinlar/Mekinist combination therapy, and promotional activity of Tafinlar and Mekinist.

Questions Answered in This Report:

  • What is the awareness of and familiarity with Tafinlar and Mekinist among medical oncologists?

  • What are the perceived clinical advantages and disadvantages of Tafinlar, Mekinist, and Tafinlar in combination with Mekinist compared to other marketed agents used in malignant melanoma?

  • What is surveyed physicians level of satisfaction with Tafinlar and Mekinist?

  • Where will Tafinlar, Mekinist , and Tafinlar in combination with Mekinist fit into the treatment algorithm for patients with malignant melanoma?

  • What promotional messages are being employed by GlaxoSmithKline, according to surveyed medical oncologists?

  • How are medical oncologists implementing biomarker testing associated with Tafinlar and Mekinist?


Sample Methodology:

~80 medical oncologists complete a 45-minute online quantitative survey with several open-ended questions for qualitative feedback. In addition, ~10 physicians participate in a 30-minute qualitative interview.

To qualify, respondents must meet the following criteria:

- Minimum of 25 malignant melanoma cancer patients under their per-sonal management per month.

- Have been in practice a minimum of 2 years and a maximum of 30 years

- More than 75 percent of professional time spent in clinical practice (academic hospital allowed 50 percent of time)


- Final report in PowerPoint format

- Access to author

Physician Research:

Medical Oncologists

Key Drugs Covered:

Tafinlar, Mekinist, Yervoy, Zelboraf, dacarbazine, Temador

Key Companies Mentioned:

- GlaxoSmithKline

- Roche / Genentech

- Bristol-Myers Squibb

Related Reports:

- TreatmentTrends®: Malignant Melanoma (EU) 2013

- TreatmentTrends®: Malignant Melanoma (US) 2013

- DecisionBase®: Malignant Melanoma (unresectable)

- Pharmacor®: Malignant Melanoma

- Pharmacor®: Biomarker-Driven Prescribing

- Pharmacor®: Immunotherapies

- PatientBase®: Malignant Melanoma in G7, and Brazil, China, India, Mexi-co, Russia, South Korea, and Turkey

- Physician & Payer Forum® (US): Biomarker-Driven Prescribing in Oncol-ogy: Physician and Payer Insights on Evolving Trends in Key Indications

- Physician & Payer Forum® (EU): Securing Favorable Reimbursement Status in the EU5 Oncology Markets: Evolving Physician and Payer Per-spectives on Biomarker-Driven Prescribing in Oncology

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