MARKET OVERVIEW
Hidradenitis suppurativa (HS) is a chronic relapsing inflammatory disorder affecting hair follicles. Humira is the only FDA-approved therapy for the disease; its use is limited—based on the label—to patients with moderate to severe disease. In addition, a variety of therapies (e.g., antibiotics, hormonal agents, retinoids, corticosteroids) are prescribed off-label for HS. Alternative biologics may also be used off-label in patients with more-severe disease who do not respond to Humira (e.g., Janssen’s Stelara). The HS pipeline holds a diverse array of therapies with unique mechanisms of action, such as IL-17 inhibitors (Novartis’s Cosentyx), IL-23 inhibitors (AbbVie’s Skyrizi and Janssen’s Tremfya), IL-1 inhibitors (bermekimab), and JAK-1 inhibitors (INCB054707). If proven efficacious, these agents will enjoy huge commercial opportunity because of the immense unmet need in this space.
QUESTIONS ANSWERED
Geography
United States Primary Research 3 KOL interviews in October 2019
Key COMPANIES Covered
AbbVie, Novartis, Janssen, XBiotech, Incyte
Key Drugs Covered
Humira, Cosentyx, Skyrizi, Tremfya, Remicade, Stelara, metformin, spironolactone, clindamycin, rifampicin, bermekimab, INCB054707
PRODUCT DESCRIPTION
Executive Insights provides indication-specific market intelligence with world-class epidemiology, keen insight into current treatment paradigms, biotherapeutic pipelines, key clinical unmet needs, and competitive landscapes, supported by primary and secondary research. This solution provides succinct insights to any biopharma function or business professional looking to quickly grasp a new indication of interest.