Myasthenia gravis (MG) is an acquired disorder of neuromuscular transmission, which occurs due to the production of pathogenic autoantibodies that bind to components of the neuromuscular junction, disrupting nerve signaling and leading to muscle weakness and fatigue. Acetylcholinesterase inhibitors (e.g., pyridostigmine) and short- and long-term immunosuppressants (e.g., prednisone, mycophenolate mofetil, and azathioprine) are the most commonly prescribed agents to manage MG symptoms. However, the MG pipeline is starting to bring novel therapies with unique MOAs to the market, highlighted by the 2017 FDA approval of eculizumab (Soliris). Because we expect multiple therapies to enter the U.S. MG market in the near future, this report offers insights on the projected launch of emerging therapies, company involvement, market predictions, and unmet need to help new players better understand the market niche for their emerging products.
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Product description:
Executive Insights provides indication-specific market intelligence with world-class epidemiology, keen insight into current treatment paradigms, biotherapeutic pipelines, key clinical unmet needs, and competitive landscapes, supported by primary and secondary research. This solution provides succinct insights to any biopharma function or business professional looking to quickly grasp a new indication of interest.
Release date: July 2021
Geography: United States
Primary Research: 3 KOL interviews in May 2021
Key companies covered: Alexion, Genentech / Roche, Argenx, Catalyst, UCB, Horizon, Takeda, Immunovant and, Janssen
Key drugs covered: Soliris, rituximab, efgartigimod, amifampridine, rozanolixizumab, zilucoplan, Ultomiris (ravulizumab), Uplizna (inebilizumab), mezagitamab, IMVT-1401, and nipocalimab