Genomic aberration status, histology, performance status, and stage of disease are key factors that influence the treatment of non-small-cell lung cancer (NSCLC). The characterization of biomarker-defined patient populations and the FDA and EC approval of a number targeted therapies in 2015 have positioned NSCLC at the forefront of personalized medicine in oncology, and have resulted in an evolving treatment landscape for the disease. This analysis provides insight on current use of approved therapies for NSCLC in the EU5 and oncologists’ perception of these therapies.

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