Acute myeloid leukemia (AML) is the most common form of adult leukemia but has the lowest five-year overall survival rates of all blood cancers. Historically, AML treatment in China has been dominated by chemotherapy; however, the approval of Celgene’s Vidaza (azacitidine) in 2017 and the expected approvals in China between 2020 and 2023 of several therapies available in Western markets will transform the AML treatment landscape. The entry of novel agents into the treatment paradigm will enable increasingly personalized treatment. However, several areas of unmet need remain. Notably, significant commercial opportunity existsfor innovative agents to treat patients unfit for intensive chemotherapy induction and relapsed/refractory AML patients. Additionally, with the ongoing reforms in China’s regulatory and access and reimbursement landscape, multinational companies are more likely to be encouraged to enter this market.

  • How large is China’s drug-treatable AML population, and how will drug-treatment rates change during the forecast period?
  • Which are the most commercially relevant drugs in China’s AML market and why?
  • What are interviewed experts’ insights into current treatment options?
  • What are the market access considerations for key therapies in the AML pipeline in China? What sales/uptake could they secure in AML? What are interviewed experts’ opinions of key emerging therapies?
  • What are the key drivers and constraints in the Chinese AML therapy market, and how will the market evolve over the forecast period?

PRODUCT DESCRIPTION

China In-Depth offers comprehensive market intelligence, including world-class epidemiology, keen insight into the China-specific A&R environment, current treatment paradigms, in-depth pipeline assessments, and drug forecasts supported by detailed primary and secondary research. This solution helps companies gauge commercial outlooks and optimize clinical development, subpopulation targeting, physician messaging, and overall long-term strategy in China.

Release date

February 2020

Geography

China

Primary research

Qualitative and quantitative insights from five thought-leading hematologist-oncologists in China, supported by survey data collected for this and other DRG research.

Epidemiology

Diagnosed prevalence of AML in urban versus rural China; clinically relevant and market-relevant drug-treatable populations .

Forecast

10-year, annualized, drug-level sales and patient shares of key AML regimens through 2029, based on primary and secondary market research to formulate bottom-up assumptions.

Emerging therapies

Phase III/PR: 8 drugs; Phase II: 5 drugs; coverage of select preclinical and Phase I products.

Table of contents

  • Acute Myeloid Leukemia - Geographic Focus: China - Acute Myeloid Leukemia | China In-Depth | China

Author(s): Amardeep Singh, M.Pharma; Oliver Blandy

Amardeep is a Senior Analyst in Decision Resources Group’s China-In-Depth team. In this role, he specializes in disease landscape and forecast reports based on a range of indications and therapy areas and focused specifically on the China healthcare market.

Prior to joining Decision Resources Group, Amardeep has worked with WNS Global Services for more than 5 years, where he worked in commercial analytics team to support Respiratory franchise of one of the top ten global pharma company. He also worked with GlobalData for 1.5 years and authored the syndicated reports on Rare, Ophthalmology and Psychiatric disorders. He earned a master’s degree in Pharmaceutical Management from University of Delhi and Bachelor of Pharmacy from Guru Gobind Singh Indraprastha University (GGSIPU), New Delhi.

 

Oliver Blandy, BSc PGCE MSc, joined Decision Resources Group (DRG) as an Associate Epidemiologist in 2017. He focuses on the epidemiology of cancer.

Oliver holds an MSc from the University of Bristol where he specialized in Nutrition, Physical Activity and Public Health. He also holds a BSc in Chemistry and has a Post Graduate Certificate in Education (PGCE), both from the University of Bristol and taught general science and Advanced Chemistry in high school for two years.

Before joining the team at DRG, Oliver worked as a Research Assistant for Imperial College London where he was the lead for several studies within an NIRH funded research group that investigated healthcare associated infections and antimicrobial resistance.


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