Heart failure is a major public health burden in China. With a rapidly rising urban population and a growing trend in unhealthy lifestyles, heart failure is expected to affect a sizable population in the country. Although the treatment of acute heart failure (AHF) is dominated by older, cost-effective generic drugs, we expect the growing uptake of recently approved SGLT-2 inhibitors—dapagliflozin (Bristol Myers Squibb’s Farxiga) and empagliflozin (Boehringer Ingelheim’s Jardiance)—to boost the heart failure market. However, a significant unmet need exists for the treatment of chronic heart failure (CHF) with preserved ejection fraction, where treatment options are limited, representing an opportunity for drug developers. In addition, the ongoing reforms in the regulatory and A&R landscape of China are expected to encourage MNCs to enter the heart failure market.


  1. How large is China’s drug-treatable heart failure population, and how will the drug-treatment rate change during the forecast period?
  2. What are the most commercially relevant drugs in China’s heart failure market, and why? What are interviewed experts’ insights into current treatment options? Which clinical needs remain unfulfilled?
  3. What are the key market access considerations for key therapies in the heart failure pipeline in China? What sales/uptake could they secure in heart failure?
  4. What are the key drivers and constraints in the Chinese heart failure market, and how will the market evolve over the forecast period?


China In-Depth offers comprehensive market intelligence, including world-class epidemiology, keen insight into the China-specific A&R environment, current treatment paradigms, in-depth pipeline assessments, and drug forecasts supported by detailed primary and secondary research. This solution helps companies gauge commercial outlooks and optimize clinical development, subpopulation targeting, physician messaging, and overall long-term strategy in China.


July 2020




Country-specific qualitative and quantitative insights driven by 5 thought-leader interviews and 50 surveys with cardiologists Supported by survey data collected for this and other DRG research epidemiology Diagnosed prevalence of heart failure in urban versus rural China; clinically relevant and market-relevant drug-treatable populations.


10-year, annualized, drug-level sales and patient shares of key heart failure regimens through 2029, based on primary and secondary market research to formulate bottom-up assumptions


Phase III/PR: 5+ drugs; Phase II: 3 drugs; coverage of select Phase I products

Table of contents

  • Heart Failure - Geographic Focus: China - Heart Failure | China In-Depth | China

Author(s): Akash Saini, Ph.D.; Sunali D. Goonesekera, SM

Akash is a Principal Analyst in the China In-Depth team at Decision Resources Group. Since 2016, he has specialized in a range of indications including rare disease indications such as DMD, ALS, ITP, IPF, JIA, and retinitis pigmentosa. He has authored Disease Landscape & Forecast reports, Access & Reimbursement reports, and Treatment Algorithm reports based on primary market research and real-world evidence. Prior to joining DRG, Akash was a post-doctoral fellow at the University of Massachusetts Medical School. He has a Ph.D. from the International Centre for Genetic Engineering and Biotechnology, New Delhi.

Sunali Goonesekera is an Associate Epidemiologist at Decision Resources Group.

Sunali holds a Master’s degree in Epidemiology from the Harvard School of Public Health and a B.A. in Biology (Honors) from Dartmouth College. Prior to joining Decision Resources Group, Sunali conducted epidemiological research and lead authored two manuscripts on racial/ethnic disparities in metabolic diseases at the New England Research Institutes. She has contributed to multiple publications in peer-reviewed journals in epidemiology and in the biological sciences.

Related Reports

Heart Failure - Landscape & Forecast - Disease Landscape & Forecast

Heart failure (HF) is categorized into acute or chronic, and both settings are the focus of this report. While much progress has been made in the pharmacological management of HF, it mainly re...

View Details

Heart Failure - Current Treatment - Detailed, Expanded Analysis - Chronic Heart Failure - Preserved Ejection Fraction - Treatment Algorithms - Claims Data Analysis - US

Although heart failure with preserved ejection fraction (HFpEF) accounts for approximately half of all chronic heart failure cases and even though our understanding of the disease’s pathophys...

View Details

Heart Failure - Current Treatment - Detailed, Expanded Analysis - Chronic Heart Failure - Reduced Ejection Fraction - Treatment Algorithms - Claims Data Analysis - US

Drug treatment of chronic heart failure (CHF) with reduced ejection fraction (HFrEF)...

View Details

Heart Failure - Current Treatment - Detailed, Expanded Analysis: Chronic Heart Failure - Treatment Algorithms: Claims Data Analysis (US)

First-line treatment of chronic heart failure (CHF) usually involves an angiotensin-converting enzyme (ACE) inhibitor, an oral beta blocker, and an oral diuretic. The addition of a second- or third...

View Details