Alopecia areata (AA) is an inflammatory autoimmune skin disease characterized by targeting of anagen hair follicles by the host immune system resulting in varying degrees of hair loss. Topical corticosteroids and topical contact allergens are commonly prescribed to treat AA; however, AA treatment guidelines are sparse, as is clinical evidence supporting the efficacy of current therapeutic options. As the AA pipeline fills in (e.g., Pfizer’s PF-6700841, Incyte’s Jakafi), this content will offer insights from real-world claims data into prescribing trends in AA to help new players seeking to better understand current treatment practices in AA and define the market niche for their emerging product.

QUESTIONS ANSWERED

  • What patient shares do key therapies and brands garner by line of therapy in newly diagnosed AA patients? What are the quarterly trends in prescribing among recently treated and newly diagnosed AA patients?
  • How have finasteride, minoxidil, and corticosteroids been integrated into the treatment algorithm, and what is their source of business? Do JAK inhibitors (e.g., Incyte’s Jakafi, Eli Lilly’s Olumiant) see off-label use in AA?
  • What percentage of AA patients receive drug therapy within one year of diagnosis, and how quickly? What percentage of patients progress to later lines of therapy within one year of diagnosis?
  • What percentage of AA patients are treated with monotherapy vs. combination therapy? What are the most commonly used drug combinations?
  • What are the product-level compliance and persistency rates among drug-treated patients?

CONTENT HIGHLIGHTS

  • Geographies: United States
  • Real-World Data: Longitudinal patient-level claims data analysis
  • Key Drugs Covered: Minoxidil, anthralin, finasteride, Xeljanz, Jakafi, Olumiant, clobetasol propionate, Elidel
  • Key Analysis Provided: brand/therapy usage across longitudinal patient sample, newly diagnosed patient analysis, treatment initiation and progression, line of therapy analysis, combination therapy analysis, source of business for recently treated patients, persistency and compliance analysis, product-level patient flow charts

PRODUCT DESCRIPTION

  • Treatment Algorithms: Claims Data Analysis provides detailed, quantitative analysis of the treatment journey and brand usage across lines of therapy and overall using real-world, patient-level claims data, so you can accurately assess your source of business, benchmark usage against competitors, and quantify areas of opportunity for your marketed or emerging brand.