Pediatric asthma pharmacotherapy has two main goals: to address underlying airway inflammation and to promote bronchodilation. Physicians use two types of therapy to achieve these goals—maintenance therapy (e.g., a LABA/ICS, such as GSK’s Advair or AstraZeneca’s Symbicort) and rescue therapy (e.g., a SABA, such as albuterol)—and most pediatric asthma patients receive more than one drug to treat their condition. Maintenance and rescue therapy for pediatric asthma consists of established agents; however, the first branded-generic LABA/ICS FDC (Teva’s AirDuo and its generic), the first LAMA (BI’s Spiriva), and several novel biologics (e.g., GSK’s Nucala) were recently added to the arsenal of drugs to treat pediatric asthma. The availability of these and other agents will expand physicians’ choice of treatments and fuel increasing competition in the asthma therapy market.
- What patient shares do key therapies and brands garner by line of therapy in newly diagnosed pediatric asthma patients? What are the quarterly trends in prescribing among recently treated and newly diagnosed pediatric asthma patients?
- How have newer pediatric asthma therapies, such as Spiriva and Nucala, been integrated into the treatment algorithm, and what are their sources of business?
- What percentage of pediatric asthma patients receive drug therapy within 365 days of diagnosis and how quickly? What percentage of patients progress to later lines of therapy within 365 days of diagnosis?
- What percentage of pediatric asthma patients are treated with monotherapy versus combination therapy? What are the most commonly used combinations?
- What are the product-level compliance and persistency rates among drug-treated patients?
- United States.
- Longitudinal patient-level claims data analysis.
Key Drugs Covered
- Advair, Symbicort, Dulera, Breo, Spiriva, Xolair, Nucala, Qvar, ProAir, montelukast sodium.
Key Analysis Provided
- Brand/therapy usage across longitudinal patient sample.
- Newly diagnosed patient analysis.
- Treatment initiation and progression.
- Line of therapy analysis .
- Combination therapy analysis.
- Source of business for recently treated patients.
- Persistency and compliance analysis.
- Product-level patient flowcharts.
Treatment Algorithms: Claims Data Analysis provides detailed, quantitative analysis of the treatment journey and brand usage across lines of therapy and overall using real-world, patient-level claims data so that marketers can accurately assess their source of business, benchmark usage against competitors, and quantify areas of opportunity for their marketed or emerging brand.
- Detailed, Expanded Analysis: Treatment Algorithms: Claims Data Analysis - Pediatric Asthma (US)
- Treatment Algorithms: Claims Data Analysis in Pediatric Asthma (US) April 2019
Author(s): Shubhendu Ghosh, PhD
Shubhendu Ghosh, is a Business Insights Analyst on the Immune and Inflammatory Disorders team at Decision Resources Group, with a primary focus on asthma. Prior to joining DRG, Shubhendu was an Associate Editor at Nature Structural & Molecular Biology and a Copy Editor at Nature Medicine. He was also a Scientific and Developmental Editor at Nature Research Editing Service. Shubhendu received his in Biomedical Sciences from the University of Massachusetts Medical School after completing a B. Sc. in Microbiology from Delhi University and an M. Sc. In Biotechnology from Madurai Kamaraj University.