MARKET OUTLOOK

Asthma pharmacotherapy has two main goals: to address underlying airway inflammation and promote bronchodilation. Physicians use two types of therapy to achieve these goals, maintenance therapy (e.g., a LABA/ICS, such as GSK’s Advair or AstraZeneca’s Symbicort) and rescue therapy (e.g., a SABA, such as albuterol), and most asthma patients will receive more than one drug to treat their condition. While there are multiple well-established agents available for both maintenance and rescue treatment, over the past two years, the asthma treatment landscape has witnessed the approval of the first branded-generic LABA/ICS FDC (i.e., Teva’s AirDuo and its generic), the first LAMA (i.e., BI’s Spiriva), and two novel biologics (i.e., GSK’s Nucala and Teva’s Cinqair). The availability of these agents has helped to expand physicians' treatment arsenal and fuel increasing competition in the asthma market.

QUESTIONS ANSWERED

  • What patient share do key therapies and brands garner by line of therapy in newly diagnosed asthma patients? What are the quarterly trends in prescribing among recently-treated and newly diagnosed asthma patients?
  • How have newer inhaled asthma therapies, such as Breo, Spiriva, Nucala, and Cinqair been integrated into the treatment algorithm?
  • What proportion of asthma patients receive drug therapy within 365 days of diagnosis, and how quickly? What percentage of patients progress to later lines of therapy within 365 days of diagnosis?
  • What percentage of asthma patients are treated with monotherapy versus combination therapy? What are the most widely used combination therapies? · What are the product-level compliance and persistency rates among drug-treated patients with asthma?

PRODUCT DESCRIPTION

Treatment Algorithms: Claims Data Analysis provides detailed analysis of brand usage across different lines of therapy using real-world data patient-level claims data so you can accurately assess your source of business and quantify areas of opportunity for increasing your brand share.

Table of contents

  • Detailed, Expanded Analysis: Treatment Algorithms: Claims Data Analysis (US)
    • Treatment Algorithms: Claims Data Analysis in Asthma

Author(s): Elena Kozhemyakina, PhD

Elena Kozhemyakina, PhD, is a Senior Business Insight Analyst at Decision Resources, Inc., specializing in pharmaceutical market analysis of the immune system disorders with expertise in Systemic Lupus Erythematosus, asthma, Crohn’s disease and ulcerative colitis. Prior to joining Decision Resources, Dr. Kozhemyakina completed a postdoctoral fellowship at Harvard Medical School, where she investigated molecular mechanisms involved in limb patterning, cartilage formation and pathogenesis of osteoarthritis. She published multiple peer-reviewed papers focused on molecular signalling of developmental disorders.


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