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Prostate cancer is the most common cancer among men in developed countries. Hormonal agents are the main treatment for prostate cancer and are routinely used throughout the course of the disease. Zytiga (Johnson & Johnson/Janssen Biotech/Janssen-Cilag/AstraZeneca’s abiraterone) and Xtandi (Pfizer/Astellas Pharma’s enzalutamide) are cornerstone treatments of metastatic castrate-resistant prostate cancer (mCRPC) and several clinical trials are evaluating their role in earlier stages of the disease. The late-phase pipeline for mCRPC has also become more dynamic with four PARP inhibitors: AstraZeneca’s Lynparza (olaparib), Clovis Oncology’s Rubraca (rucaparib), Tesaro/Janssen Biotech’s Zejula (niraparib), and Pfizer’s Talzenna (talazoparib); two immune checkpoint inhibitors, Roche/Genentech/Chugai’s Tecentriq (atezolizumab) and Merck Sharp & Dohme’s Keytruda (pembrolizumab); a kinase inhibitor, Array BioPharma/Roche/Genentech /Chugai’s ipatasertib; and a radioligand therapy, Endocyte’s 177Lu-PSMA-617, entering Phase III development.
Disease Landscape & Forecast: Comprehensive market intelligence providing world-class epidemiology, keen insight into current treatment paradigms, in-depth pipeline assessments, and drug forecasts supported by detailed primary and secondary research.
Markets covered:United States, France, Germany, Italy, Spain, United Kingdom, and Japan.
Primary research: More than 20 country-specific interviews with thought-leading medical oncologists, supported by survey data collected for this and other DRG research.
Key companies: Johnson & Johnson, Janssen Biotech, Janssen-Cilag, AstraZeneca, Pfizer, Astellas Pharma, Sanofi, Roche, Tesaro, Clovis Oncology, Endocyte, Merck Sharp & Dohme.
Key drugs: Xtandi (enzalutamide), Zytiga (abiraterone), Erleada (apalutamide), Xofigo (radium-223), Jevtana (cabazitaxel), docetaxel, Yonsa (abiraterone acetate), Lynparza (olaparib), Rubraca (rucaparib), Talzenna (talazoparib), Zejula (niraparib), Tecentriq (atezolizumab), Keytruda (pembrolizumab), 177Lu-PSMA-617.
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Carolina do Pazo, is a Business Insights Analyst in the oncology division at Decision Resources Group. Prior to joining DRG, she completed a MSc in Biotechnology, Bioprocessing and Business Management with distinction at the University of Warwick, as a Chevening scholar. She also earned her first-class BSc and BEng in Biotechnology from the Universidad ORT. Ms. do Pazo has worked as a Research Scientist at the Institut Pasteur de Montevideo, analysing the ageing process of yeast cells, and has been part of a project between Indiana University and Universidad ORT that analysed the production of nanohybrids for drug delivery systems applications.
Narendra is an associate epidemiologist within the epidemiology team at Decision Resources Group. Narendra specializes in developing epidemiological forecasts for multiple indications within the DRG syndicated portfolio. His qualifications include an MPH with specialization in Health Policy, Economics and Finance from the Tata Institute of Social Sciences, Mumbai, and a Bachelor’s degree in Dentistry from the Rajasthan University of Health Sciences.