MARKET OUTLOOK
Hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP) are among the most common and serious infections in the hospital setting. HABP/VABP due to carbapenem-resistant organisms (CROs) are particularly difficult-to-treat and life-threatening. No current antibiotic was specifically developed for CROs. Allergan/Pfizer’s Avycaz/Zavicefta and Melinta’s Vabomere address some of the unmet need in this area, but most current treatments are combinations of generically available antibiotics and have significant side effects and/or suboptimal efficacy.
QUESTIONS ANSWERED
PRODUCT DESCRIPTION
Unmet Need supports clinical development decisions by identifying key attributes and assessing areas of unmet need for a specific disease or subpopulation. Based on surveys with U.S. and European physicians, this report provides insight into key treatment drivers and goals, the performance of current therapies, and the remaining commercial opportunities. Two market scenarios are profiled in detail by DRG experts, and additional customized market scenarios can be evaluated with the corresponding TPP simulator.
Markets covered: United States, United Kingdom, France, Germany
Primary research: Survey of 61 U.S. and 30 European ID specialists fielded in February 2019
Key drugs: Avycaz/Zavicefta, Vabomere, tigecycline, meropenem, imipenem/cilastatin, colistin
Key metrics included: