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Research & Reports

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Diabetic Macular Edema / Diabetic Retinopathy | Access & Reimbursement | Detailed, Expanded Analysis (US)

Diabetic Macular Edema / Diabetic Retinopathy | Access & Reimbursement | Detailed, Expanded Analysis (US)

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Vascular endothelial growth factor (VEGF) inhibitors—approved agents Eylea (Regeneron) and Lucentis (Roche/Genentech), and off-label Avastin (Roche/Genentech)—are the treatment mainstays for diabetic macular edema (DME). Allergan’s Ozurdex and Alimera Sciences’ Iluvien, two long-acting corticosteroid implants, are also used to treat DME. The market heated up in April 2017 when the label of Lucentis 0.3 mg was expanded to treat patients with diabetic retinopathy (DR) without DME. Factoring in the anticipated approval of Eylea for nonproliferative DR patients without DME in the United States, as well as the expected availability of biosimilars of Lucentis 0.5 mg and Eylea and emerging therapies for DME, this report delivers actionable insights to help companies best position their DME/DR products to succeed in the U.S. access and reimbursement environment.

Questions Answered

  • Does coverage of therapies for DME differ on MCOs’ largest Medicare Advantage and commercial insurance plans? How do various cost-control measures impact prescribing of current therapies for DME?
  • How do pharmacoeconomic/health economic outcomes data impact formulary decision-making for drugs for DME?
  • Do physicians expect to prescribe the emerging therapies abicipar pegol (Allergan), Luminate (Allegro Ophthalmics), and RG-7716 (Roche) to their DME patients? What factors would influence preferred coverage of these agents on the MCOs’ largest risk-based commercial plans?
  • How is the expected availability of biosimilars of Lucentis 0.5 mg and Eylea likely to impact access to and reimbursement of the originator branded therapies for DME?

Product Description

Access & Reimbursement provides in-depth insight regarding the impact of payer policy on physician prescribing behavior so you can build your market access strategy and optimize your brand positioning.

Markets covered: United States

Primary research:

  • Survey of 104 ophthalmologists/retinal specialists in the United States.
  • Survey of 30 U.S. managed care organization (MCO) pharmacy and medical directors (PDs/MDs).

Key companies: Roche/Genentech, Regeneron, Alimera Sciences, Allergan, Allegro Ophthalmics

Key drugs: Avastin, Eylea, Lucentis, Iluvien, Ozurdex, RG-7716, Luminate, abicipar pegol

Content highlights:

  • Reimbursement and contracting.
  • Access and prescribing.
  • Special topics.
  • Opportunities and challenges for emerging therapies.

Table of contents

  • Detailed, Expanded Analysis (US)
    • Access & Reimbursement - Diabetic Macular Edema/Diabetic Retinopathy US [June 2018]

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  • Pub Date: June 2018
  • Author(s): Himanshu Jain, M.S. Pharm
  • Himanshu is a Lead Analyst in the CNS/Ophthalmology team at Decision Resources Group, and has authored content for indications including age-related macular degeneration, diabetic retinopathy/diabetic macular edema, and unipolar depression. He comes with eight years of experience working on commercial assessment projects, including opportunity assessments, market intelligence, disease narratives, epi-based forecasts, patent research, and social media analysis, across multiple therapy areas. He holds a degree in Pharmacology from the National Institute of Pharmaceutical Education and Research (NIPER) in India and an Executive Post-Graduate Diploma in International Business from the Indian Institute of Foreign Trade.

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