DRG Epidemiology’s coverage of epilepsy comprises epidemiological estimates of key patient populations in 45 countries. We report both the incidence and the prevalence of epilepsy for each country, as well as annualized case counts projected to the national population.

Most patient populations are forecast over a period of 20 years for the major mature pharmaceutical markets and 10 years for the other countries covered. In addition to forecasting incident and prevalent patient populations, we forecast the number of drug-treatment opportunities in specific lines of therapy in the United States, Europe, and Japan.

DRG Epidemiology’s epilepsy forecast will answer the following questions:

  • Of all people with epilepsy, how many in the countries have been formally diagnosed?
  • Of all people diagnosed with epilepsy, how many in each country across the major mature pharmaceutical markets are drug-treated?
  • How will demographic trends, such as population aging and improving life expectancy, affect the epidemiology of epilepsy over the forecast period?

All forecast data are available on the DRG Insights Platform in tabular format, with options to download to MS Excel. All populations are accompanied by a comprehensive description of the methods and data sources used, with hyperlinks to external sources. A summary evidence table generated as part of our systematic review of the epidemiological literature is provided for full transparency into research and methods.

In addition to the total number of cases for each forecast year, DRG Epidemiology provides at least ten years of forecast data for the following epilepsy subpopulations:

  • Diagnosed prevalence of Lennox-Gastaut cases by intractable epilepsy.
  • Diagnosed prevalent cases by risk of acute repetitive seizures.
  • Diagnosed prevalent cases by drug-treatment status.
  • Diagnosed prevalent cases by seizure level.
  • Diagnosed prevalence ofLennox-Gastaut cases by type of seizure.
  • Diagnosed prevalence of Lennox-Gastaut cases by status epilepticus.
  • Drug-treated prevalent cases by drug-resistance status.
  • Scn1a mutation status.
  • Status epilepticus status.

Note: Coverage may vary by country.

Table of contents

  • Europe Data
    • Introduction
      • Key Findings
        • Key Findings
      • Overview
        • Prevalence of Epilepsy per 1,000 Among People of All Ages in 2018 and 2038
        • Relative Sizes of the Factors Contributing to the Trend in Prevalent Cases of Epilepsy over the Next 20 Years
        • Analysis of Diagnosed Prevalent Cases of Epilepsy in the Countries Under Study in 2018 by Type of Seizure
    • Epidemiology Data
    • Methods
      • Diagnosed Prevalent Cases
      • Seizure Type
      • Drug Resistance
      • Acute Repetitive Seizures
      • Percentage Drug-Treated
      • Diagnosed Prevalence of Dravet Syndrome
      • Diagnosed Incidence of Dravet Syndrome
      • Dravet Syndrome with Status Epilepticus
      • Dravet Syndrome with SCN1A Mutation
    • Reference Materials
      • Literature Review
      • Risk/Protective Factors
        • Risk/Protective Factors
      • Bibliography

Author(s): Shilpa Thakur; Abey John, MPH

Shilpa Thakur is a medical graduate with a from the Postgraduate Institute of Medical Education and Research with a specialization in epidemiology and biostatistics. She specializes in developing epidemiological forecasts for the multiple indications within the DRG syndicated portfolio. Prior to joining Decision Resources, she monitored HIV sentinel surveillance 2016-2017 in Himachal Pradesh. She also has worked on to see the patterns of Antimicrobial resistance in India.  

Abey John is a medical graduate with a Master’s in Public Health and has been associated with DRG since September 2015. He works with a global team of epidemiologists in performing systematic reviews of assigned diseases and prepare forecast models for clients. He also is involved in producing analyses for pharmaceutical drug developers on the descriptive epidemiology of major drug indications in mature and developing markets and have an overall experience of three years working in different healthcare sectors across the country. Prior to joining DRG, Abey had been working with Jhpiego (an affiliate of Johns Hopkins Medical University) in implementing Family Planning Health Programs in India with collaborating with the Government of India. He also has worked with a grassroots level NGO as a health team manager which worked for the benefit of the rural population living in the foothills of the Himalayas.

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