Peripheral arterial disease (PAD) is a complex manifestation of underlying atherosclerotic disease and is closely associated with coronary and cerebrovascular disease. Current treatment practice largely focuses on both lifestyle modifications and the use of statins, antihypertensives, and antiplatelet agents as cornerstone therapies to prevent events such as MI and stroke in these patients. The emergence of PCSK9 inhibitors to achieve aggressive LDL cholesterol lowering on top of statins is another therapeutic option for PAD patients.
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