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Research & Reports

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Systemic Lupus Erythematosus | Landscape & Forecast | Disease Landscape & Forecast

Systemic Lupus Erythematosus | Landscape & Forecast | Disease Landscape & Forecast

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SLE is an autoimmune condition characterized by varied symptoms and multiple organ involvement, making it a complex disease, which is difficult to manage. Moreover, challenges in clinical trial design and in understanding potential market for SLE therapies often impede drug development, leading to high failure rates of pipeline agents. To date, Benlysta is the only approved biologic for SLE, which caters to a specific SLE population, leaving high unmet need in the SLE space. Pharmaceutical companies have identified the hidden commercial opportunity in this area and, currently, SLE pipeline has several agents in late-phase and many more in early-phase development. The SLE Disease Landscape and Forecast offers detailed insights into current medical practices, key unmet needs, and new developments in SLE space, along with an analysis of opportunities and obstacles faced by emerging agents.

Questions Answered:

  • How large is the drug-treated SLE population, and how is it going to emerge during the 2016-2026 forecast period?
  • How large is the treatable SLE population and how will diagnosis/drug-treatment rates change over time?
  • What is the current state of treatment in SLE? Which are the most important drugs and why? What are interviewed experts’ insights on current treatment options? What are the key unmet needs in SLE?
  • Which novel therapies are most promising, and what sales/uptake could they secure in SLE? What therapies of note are progressing in earlier phases?
  • What are the drivers and constraints in the SLE market, and how will the market evolve over the forecast period?

Scope:

Markets covered: United States, France, Germany, Italy, Spain, United Kingdom, and Japan.

Primary research: Approximately 30 country-specific interviews with rheumatologists and nephrologists.

Epidemiology: Diagnosed prevalence of SLE by country and subpopulations (nonrenal SLE and lupus nephritis).

Population segments in market forecast: Total population, nonrenal SLE population, renal SLE (LN) population.

Emerging therapies: Phase II: 20 drugs; Phase III: 6 drugs; Coverage of 7 select preclinical and Phase I products.

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  • Pub Date: August 2018
  • Author(s): Mohit Nasa, MBA; Sunali D. Goonesekera, SM
  • Mohit Nasa is a Lead Insights analyst on the Immune and Inflammatory team at Decision Resources Group and has authored content for indications like asthma and rheumatoid arthritis. He holds a Bachelor’s degree in Pharmacy and has earned his MBA in marketing and CRM from Amity Business School. Prior to joining DRG, Mohit worked as a Senior Business analyst at Novartis where he was responsible for end to end market assessment, reporting analytics and related projects for Novartis’s asthma brand Xolair. Mohit has also worked as Brand Manager at Ozone pharma and an Account Manager for IMS Health.

  • Sunali Goonesekera is an Associate Epidemiologist at Decision Resources Group. Sunali holds a Master’s degree in Epidemiology from the Harvard School of Public Health and a in Biology (Honors) from Dartmouth College. Prior to joining Decision Resources Group, Sunali conducted epidemiological research and lead authored two manuscripts on racial/ethnic disparities in metabolic diseases at the New England Research Institutes. She has contributed to multiple publications in peer-reviewed journals in epidemiology and in the biological sciences.

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