Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that surveyed cardiologists indicate that a therapy's effect on the prevention of venous thromboembolism (VTE) is the attribute that most influences their prescribing decisions for VTE prophylaxis in medically ill patients. Clinical data and the opinions of interviewed thought leaders indicate that Bayer/Johnson & Johnson's Xarelto has advantages in this attribute over Sanofi-Aventis's Lovenox, the sales-leading agent in the market.
The new report entitled Venous Thromboembolism Prophylaxis in Medically Ill Patients: Significant Opportunity Awaits Therapies Offering Improved Efficacy finds that an orally available therapy for VTE prophylaxis in medically ill patients would earn a 65 percent patient share in the United States and an 80 percent patient share in Europe, according to surveyed U.S. and European cardiologists.
In 2008, Decision Resources' proprietary clinical gold standard for VTE prophylaxis in medically ill patients was GlaxoSmithKline's Arixtra, owing largely to its efficacy. Based on available data and expert opinion, Xarelto will earn gold standard status for VTE prophylaxis in medically ill patients in 2012, following its approval for the indication in 2011.
"Xarelto has competitive advantages over Arixtra in terms of delivery and safety," said Decision Resources Analyst Christine Helliwell, Ph.D. "Xarelto's main advantage is that it causes a level of bleeding similar to that of Lovenox, whereas Arixtra suffers from a perception that it causes increased rates of bleeding over Lovenox."
About the Report
Venous Thromboembolism Prophylaxis in Medically Ill Patients: Significant Opportunity Awaits Therapies Offering Improved Efficacy is a DecisionBase 2009 report. DecisionBase 2009 is a decision-support tool that provides in-depth analysis of unmet need, physician expectations of new therapies and commercial dynamics to help pharmaceutical companies optimize their investments in drug development.
The report can be purchased by contacting Decision Resources. Members of the media may request an interview with an analyst.
About Decision Resources
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