Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that a first-line therapy for metastatic renal cell carcinoma that can increase overall survival in comparison with Pfizer's Sutent would earn a 50 percent patient share in the United States and a 35 percent patient share in Europe, according to surveyed U.S. and European oncologists.
The new report entitled Renal Cell Carcinoma (Metastatic): Axitinib's Improvements in Overall Survival will Differentiate it from Current and Emerging Therapies finds that a therapy's effect on overall survival is the attribute that most influences surveyed oncologists' prescribing decisions in metastatic renal cell carcinoma. Clinical data and the opinions of interviewed thought leaders indicate that Pfizer's axitinib has advantages over Sutent in this attribute. Sutent, the market sales leading agent, was Decision Resources' proprietary clinical gold standard in 2008 for metastatic renal cell carcinoma.
Based on available data and expert opinion, axitinib will earn gold-standard status for metastatic renal cell carcinoma in 2012 through 2017, following its approval for the indication in 2011. Interviewed experts anticipate that axitinib, which has competitive advantages and has shown impressive Phase II survival data in the second-line setting, will be more effective than Sutent.
"In the second-line setting, axitinib has shown an increase in median overall survival in clinical trials," said Decision Resources Analyst Laila Siddique. "This median overall survival is slightly longer than the overall survival observed with Sutent in the first-line setting. Axitinib's data are particularly impressive because patients receiving second-line therapies generally have a poorer prognosis than patients in the first-line setting."
About the Report
Renal Cell Carcinoma (Metastatic): Axitinib's Improvements in Overall Survival will Differentiate it from Current and Emerging Therapies is a DecisionBase 2009 report. DecisionBase 2009 is a decision-support tool that provides in-depth analysis of unmet need, physician expectations of new therapies and commercial dynamics to help pharmaceutical companies optimize their investments in drug development.
The report can be purchased by contacting Decision Resources. Members of the media may request an interview with an analyst.
About Decision Resources
Decision Resources (www.decisionresources.com) is a world leader in market research publications, advisory services and consulting designed to help clients shape strategy, allocate resources and master their chosen markets. Decision Resources is a Decision Resources, Inc. company.
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