Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, through 2018, generic erosion of key statins such as Pfizer's Lipitor/Tahor/Sortis/Cardyl (atorvastatin) and AstraZeneca's Crestor (rosuvastatin) will reduce the dyslipidemia drug market by $4 billion in the United States, France, Germany, Italy, Spain, the United Kingdom and Japan.

The new Pharmacor report entitled Dyslipidemia finds that sales of Lipitor/Tahor/Sortis/Cardyl will decline following the market entry of generic atorvastatin in 2010, which will also steal patient share from Crestor and Merck/Schering-Plough's Vytorin/Inegy. Similarly, beginning in 2016 in the U.S., the market entry of generic rosuvastatin will further constrain sales of Crestor, Vytorin/Inegy and other branded agents.

Additionally, in European markets, regulators continue their efforts to cut costs by promoting the prescription of generics by providing financial incentives for their use and regulating patient copayment systems. Similar cost-saving measures are expected in Japan, while in the U.S., managed care organizations will strongly incentivize the use of generic atorvastatin and generic rosuvastatin before approving prescription of novel fixed-dose combinations. Although generic erosion will constrain the market, the report finds that opportunity exists in the development of agents that modify lipid parameters for the growing number of patients with mixed dyslipidemia. (Mixed dyslipidemia is characterized by elevated LDL cholesterol and triglyceride levels combined with decreased levels of HDL cholesterol.)

"We forecast that approximately six percent of patients who are currently prescribed individually-formulated statins will be prescribed fixed-dose combinations containing a statin by 2018," said Decision Resources Analyst Alana Lessi. "The launch of several new fixed-dose combinations over the next few years will increase competition for patient share within this class and, as a result, new fixed-dose combinations will compete with potent statins."

About Decision Resources

Decision Resources (www.decisionresources.com) is a world leader in market research publications, advisory services and consulting designed to help clients shape strategy, allocate resources and master their chosen markets. Decision Resources is a Decision Resources, Inc. company.

About Decision Resources, Inc.

Decision Resources, Inc. is a cohesive portfolio of companies that offers best-in-class, high-value information and insights on important sectors of the healthcare industry. Clients rely on this analysis and data to make informed decisions. Please visit Decision Resources, Inc. at www.DecisionResourcesInc.com.

  All company, brand, or product names contained in this document may be      trademarks or registered trademarks of their respective holders.    Decision Resources             Decision Resources, Inc.   Christopher Comfort            Elizabeth Marshall   781-296-2597                   781-296-2563   ccomfort@dresources.com        emarshall@dresources.com 

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SOURCE: Decision Resources

CONTACT: Christopher Comfort of Decision Resources, +1-781-296-2597,
ccomfort@dresources.com, or Elizabeth Marshall of Decision Resources, Inc.,
+1-781-296-2563, emarshall@dresources.com

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