Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that surveyed cardiologists identify a therapy's effect on mortality as the attribute that most influences their prescribing decisions in the treatment of ST-elevation myocardial infarction (STEMI). Clinical data and the opinions of interviewed thought leaders indicate that The Medicines Company's Angiomax/Angiox has advantages in this attribute over Eli Lilly's ReoPro, the sales-leading agent in percutaneous coronary intervention (PCI) treatment of STEMI.
The new report entitled STEMI: Significant Opportunity Awaits Drugs That Can Reduce Mortality Rates also finds that an antiplatelet agent administered with stenting that is associated with lower rates of mortality and thrombocytopenia than ReoPro and less severe drug interactions would earn a substantial patient share in STEMI. According to surveyed U.S. and European cardiologists, this patient share would be 50 percent in the United States and 40 percent in Europe.
In 2008, Decision Resources' proprietary clinical gold standard for STEMI treated with PCI was Angiomax/Angiox. Based on available data and expert opinion, Angiomax/Angiox will retain gold-standard status for STEMI in 2017. While some therapies in development for the treatment of STEMI with PCI hold promise, most have efficacy, safety and tolerability, and/or delivery features that interviewed physicians indicate are inferior when compared with Angiomax/Angiox.
"Interviewed physicians regard Angiomax/Angiox as being highly efficacious because it is associated with significantly lower mortality rates than the standard PCI adjunctive therapy of unfractionated heparin and a glycoprotein IIb/IIIa inhibitor," said Decision Resources Analyst Jeremy Goldman, M.D. "This mortality reduction is associated with lower rates of bleeding with Angiomax/Angiox."
About the Report
STEMI: Significant Opportunity Awaits Drugs That Can Reduce Mortality Rates is a DecisionBase 2009 report. DecisionBase 2009 is a decision-support tool that provides in-depth analysis of unmet need, physician expectations of new therapies and commercial dynamics to help pharmaceutical companies optimize their investments in drug development.
The report can be purchased by contacting Decision Resources. Members of the media may request an interview with an analyst.
About Decision Resources
Decision Resources (www.decisionresources.com) is a world leader in market research publications, advisory services and consulting designed to help clients shape strategy, allocate resources and master their chosen markets. Decision Resources is a Decision Resources, Inc. company.
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