Sepsis and septic shock have been notoriously difficult indications for drug development. However, considering the high incidence of sepsis, associated high mortality, and vast unmet needs, this indication offers considerable market opportunity for pharmaceutical and biotechnology manufacturers able to develop effective therapies. Sepsis and Septic Shock is a new study from Decision Resources, Inc., that offers critical strategic analysis for companies seeking to benefit from an emerging sales opportunity for sepsis therapeutics in the billions of dollars.

  (Photo: )    Novel Therapies Have Significant Commercial Potential 

No therapies are currently marketed to treat the inflammatory and coagulation disturbances associated with sepsis and septic shock. Because of the high unmet need, both in terms of mortality and cost (ICU care), the emerging therapies targeting these pathways have vast market potential. If these agents are approved, their novelty-as the first therapeutics ever to directly affect the outcome and mortality of severe sepsis and septic shock- will provide a strong impetus for considerable and rapid uptake.

Experts in all of the seven major markets (United States, France, Germany, Italy, Spain, United Kingdom, and Japan) are particularly enthusiastic about Eli Lilly's recombinant human activated pated to greater utilization of broad-spectrum agents that can be used as monotherapy (e.g., the fluoroquinolones and carbapenems) and strong uptake of agents effective against antibiotic-resistant bacteria (e.g., novel glycopeptides, fluoroquinolones).

Sepsis and Septic Shock is part of Infectious Disease, one of six Pharmacor services that evaluate the commercial potential of drugs in research and development.

Decision Resources, Inc., is a world leader in pharmaceutical research publications, advisory services, and consulting designed to help clients shape strategy, allocate resources, and master their chosen markets. Founded as a subsidiary of Arthur D. Little, Inc., the company has provided strategic information services for 30 years. Visit the Decision Resources Web site at

Contact: Frank Sama, 781.296.2553 (telephone), 781.296.2525 (fax), or

In Europe, contact Francoise Bidart, +32.2.351.4082 (telephone), +32.2.351.2347 (fax), or

In Japan, contact Makiko Yoshimoto, +81.3.5401.2615 (telephone), +81.3.5401.2617 (fax), or


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SOURCE: Decision Resources, Inc.

Contact: Frank Sama of Decision Resources, Inc., +1-781-296-2553,