Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that Merck KGaA/Oncothyreon's Stimuvax vaccine earns Decision Resources' proprietary clinical gold standard status in 2013 and 2018 for the treatment of locally advanced non-small-cell lung cancer. Available data from Phase II clinical trials of Stimuvax have shown promising median overall survival and tumor response rates in patients when the drug is used as a maintenance therapy following chemoradiotherapy.
"Interviewed oncologists are excited about Stimuvax's Phase IIb clinical trial results in a subset of patients with locally advanced disease, and they are hopeful that the findings will be supported by positive Phase III data, especially given that ongoing studies include patients who will have a lower tumor burden than those involved in the Phase IIb trial," stated Decision Resources Analyst Janie Cox, Ph.D.
The new report entitled Locally Advanced Non-Small-Cell Lung Cancer: Targeted Agents and New Treatment Strategies Pave the Way also finds that a drug that improves median overall survival when used in conjunction with radiotherapy or chemoradiotherapy compared with etoposide (Bristol-Myers Squibb's Etopophos/Vepesid/Vepsid, Baxter's Celltop, Nippon Kayaku's Lastet)/cisplatin (Bristol-Myers Squibb's Platinol-AQ/Briplatin, Pfizer's Platosin, Nippon Kayaku's Randa, generics) plus concurrent radiotherapy for the treatment of unresectable locally advanced non-small-cell lung cancer would earn 55 percent patient share in the U.S., according to surveyed U.S. oncologists. In contrast, in Europe, such a drug would earn a lower patient share of 40 percent, according to surveyed European oncologists. Patient share of the magnitude indicated by U.S. and European oncologists would translate into healthy revenue in what is a modestly sized subpopulation of the total non-small-cell lung cancer market.
About the Report
Locally Advanced Non-Small-Cell Lung Cancer: Targeted Agents and New Treatment Strategies Pave the Way is a DecisionBase 2010 report. DecisionBase 2010 is a decision-support tool that provides in-depth analysis of unmet need, physician expectations of new therapies and commercial dynamics to help pharmaceutical companies optimize their investments in drug development.
About Decision Resources
Decision Resources (www.DecisionResources.com) is a world leader in market research publications, advisory services and consulting designed to help clients shape strategy, allocate resources and master their chosen markets. Decision Resources is a Decision Resources, Inc. company.
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SOURCE: Decision Resources
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