Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, forecasts enormous sales potential for novel cancer therapies entering the market over the next 15 years. The identification of multiple novel targets resulting in opportunities to launch numerous new and premium-priced targeted agents into the market and the increased use of combinations of well-tolerated targeted therapies will contribute to the market's growth.
According to a new Pharmacor report entitled Early Stage Anti-Cancer Drugs, five new classes of cancer drugs will jointly account for more than $20 billion in sales in 2021. The classes include inhibitors of apoptosis (lead companies in this area are Genentech, Amgen, Human Genome Sciences, and GlaxoSmithKline), inhibitors of down-stream signaling (lead companies in this area include Pfizer, Array, and Novartis), inhibitors of DNA repair (lead company in this area is AstraZeneca), inhibitors of cell cycle kinases (lead companies in this area include AstraZeneca, Merck, Cyclacel, and Vertex), and inhibitors of heat shock proteins (lead companies in this area are Kosan and Biogen Idec).
The launch of targeted therapies in cancer imposes a large economic burden on society because of their premium prices and increasing treatment durations.
"To maximize the cost-to-benefit ratio, clinicians will want to identify up front potential responders over patients unlikely to benefit from treatment," said Joanne Graham, Ph.D., therapeutic area director at Decision Resources. "And, in guarded markets, the use of premium-priced drugs will be constrained despite data to support clinical benefit."
Pharmacor is a unique family of studies that assesses a host of market- impacting factors and analyzes the commercial outlook for drugs in research and development.
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SOURCE: Decision Resources
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