Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that GlaxoSmithKline's Duodart (the fixed-dose combination of dutasteride and tamsulosin) will earn Decision Resources' proprietary clinical gold standard status in 2013 and through 2018 for the treatment of benign prostatic hyperplasia/male lower urinary tract symptoms due to its competitive advantage in overall efficacy over the current gold standard dutasteride (GlaxoSmithKline's Avodart, Taiho Pharmaceutical's Avolve).
The new report entitled Benign Prostatic Hyperplasia/Male Lower Urinary Tract Symptoms: More Convenient Therapies Targeting Improved Patient Compliance Are on the Horizon also finds that symptom improvement is the most important drug attribute influencing surveyed U.S. and European urologists' prescribing decisions in benign prostatic hyperplasia/male lower urinary tract symptoms. This finding also parallels anecdotal evidence provided by interviewed thought leaders, who indicate that alleviating symptoms is the paramount goal when treating benign prostatic hyperplasia/male lower urinary tract symptoms patients. For developers of novel therapies this means that the bar has been set high in terms of physician expectations for symptom improvement given that uroselective alpha blockers have largely fulfilled the need for a drug that relieves lower urinary tract symptoms (suggestive of benign prostatic hyperplasia) without generating serious side effects (such as orthostatic hypotension).
"To make significant inroads into the benign prostatic hyperplasia/male lower urinary tract symptoms market we believe novel agents would have to show symptom relief that is at least comparable to the relief provided by existing treatments and offer additional benefit such as relatively low rates of sexual side effects, infrequent dosing and earlier and significant improvement in disease modification," stated Decision Resources Therapeutic Area Director Melissa Stolper.
About the Report
Benign Prostatic Hyperplasia/Male Lower Urinary Tract Symptoms: More Convenient Therapies Targeting Improved Patient Compliance Are on the Horizon is a DecisionBase 2010 report. DecisionBase 2010 is a decision-support tool that provides in-depth analysis of unmet need, physician expectations of new therapies and commercial dynamics to help pharmaceutical companies optimize their investments in drug development.
About Decision Resources
Decision Resources (www.DecisionResources.com) is a world leader in market research publications, advisory services and consulting designed to help clients shape strategy, allocate resources and master their chosen markets. Decision Resources is a Decision Resources, Inc. company.
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