Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that the launch of Medarex/Bristol-Myers Squibb's ipilimumab and Pfizer's ticilimumab will significantly impact the market for treatment of malignant melanoma. According to the new report entitled New Therapies Entering the Market May Raise Hurdles: A Malignant Melanoma Study, both ipilimumab and ticilimumab offer clinicians more freedom in treatment design based on the individual patient's performance status.
The approval of ipilimumab and ticilimumab will have a significant impact on the stage IV malignant melanoma market.
"Although ipilimumab will initially target relapsing patients and ticilimumab will be used as a first-line monotherapy, ipilimumab will move into the first-line setting in combination with the commonly used chemotherapy agent dacarbazine," said Mohamed Muhsin, analyst at Decision Resources. "The availability of both agents, approved for different regimens (ticilimumab as a monotherapy; ipilimumab in combination), will give clinicians more freedom in deciding whether to incorporate a chemotherapy agent based on the individual patient's performance status, and it will help them avoid the reimbursement issues associated with prescribing off-label."
About New Therapies Entering the Market May Raise Hurdles: A Malignant Melanoma Study
New Therapies Entering the Market May Raise Hurdles: A Malignant Melanoma Study covers the current and future state of the malignant melanoma drug market. The report includes the following:
-- More than 3,000 physician responses that define drug attributes that drive prescription now and in the future. - Clinical end point tradeoffs that are most influential to physicians. - Areas of unmet need with highest potential. - Benchmark trial results for specific drug opportunities. - Patient share potential for emerging therapies and target product profiles. -- Decision Resources proprietary analysis of commercial factors that accelerate or constrain a drug's market potential. - Promotion: DTC spend, detailing intensity. - Reimbursement: formulary tier, prior approval restriction, quantity limits. - Labeling: black box warnings, approved patient segments, contraindications. - Competition: order of entry, pricing, generic entry, pipeline sales forecast. - Medical practice: decision trees, treating physician type, line of therapy. - Comparisons of the key clinical attributes of current and emerging therapies in the areas of efficacy, safety, and delivery. - Analysis and supporting data that identify the clinical "Gold Standard" now and over the next ten years. - Key insights as to which clinical end points have the greatest influence on physician decision-making.
The report can be purchased by contacting Decision Resources. Members of the media may request an interview with an analyst.
About Decision Resources
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