Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that the launch of Medarex/Bristol-Myers Squibb's ipilimumab and Pfizer's ticilimumab will significantly impact the market for treatment of malignant melanoma. According to the new report entitled New Therapies Entering the Market May Raise Hurdles: A Malignant Melanoma Study, both ipilimumab and ticilimumab offer clinicians more freedom in treatment design based on the individual patient's performance status.

The approval of ipilimumab and ticilimumab will have a significant impact on the stage IV malignant melanoma market.

"Although ipilimumab will initially target relapsing patients and ticilimumab will be used as a first-line monotherapy, ipilimumab will move into the first-line setting in combination with the commonly used chemotherapy agent dacarbazine," said Mohamed Muhsin, analyst at Decision Resources. "The availability of both agents, approved for different regimens (ticilimumab as a monotherapy; ipilimumab in combination), will give clinicians more freedom in deciding whether to incorporate a chemotherapy agent based on the individual patient's performance status, and it will help them avoid the reimbursement issues associated with prescribing off-label."

About New Therapies Entering the Market May Raise Hurdles: A Malignant Melanoma Study

New Therapies Entering the Market May Raise Hurdles: A Malignant Melanoma Study covers the current and future state of the malignant melanoma drug market. The report includes the following:

  -- More than 3,000 physician responses that define drug attributes that      drive prescription now and in the future.      - Clinical end point tradeoffs that are most influential to physicians.      - Areas of unmet need with highest potential.      - Benchmark trial results for specific drug opportunities.      - Patient share potential for emerging therapies and target product        profiles.    -- Decision Resources proprietary analysis of commercial factors that      accelerate or constrain a drug's market potential.      - Promotion: DTC spend, detailing intensity.      - Reimbursement: formulary tier, prior approval restriction, quantity        limits.      - Labeling: black box warnings, approved patient segments,        contraindications.      - Competition: order of entry, pricing, generic entry, pipeline sales        forecast.      - Medical practice: decision trees, treating physician type, line of        therapy.      - Comparisons of the key clinical attributes of current and emerging        therapies in the areas of efficacy, safety, and delivery.      - Analysis and supporting data that identify the clinical "Gold        Standard" now and over the next ten years.      - Key insights as to which clinical end points have the greatest        influence on physician decision-making.  

The report can be purchased by contacting Decision Resources. Members of the media may request an interview with an analyst.

About Decision Resources

Decision Resources, Inc. ( is a world leader in market research publications, advisory services, and consulting designed to help clients shape strategy, allocate resources, and master their chosen markets.

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  For more information, contact:   Elizabeth Marshall   Decision Resources, Inc.   781-296-2563 

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SOURCE: Decision Resources, Inc.

CONTACT: Elizabeth Marshall of Decision Resources, Inc.,

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