BURLINGTON, Mass., Aug. 6, 2014 /PRNewswire/ -- Decision Resources Group finds that at one year post-launch in the United States, over two thirds of surveyed U.S. medical oncologists have prescribed Bayer HealthCare's alpha-emitting radiopharmaceutical Xofigo. The majority of current non-prescribers indicated that they expect to prescribe Xofigo to their metastatic castrate-resistant prostate cancer (mCRPC) patients within the next six months. Notably, at one year post-launch, nearly one-half of surveyed respondents indicated that the need for referral to a licensed physician in an approved nuclear medicine facility would moderately impact their prescribing decisions for Xofigo.

Other key findings from report entitled LaunchTrends®: Xofigo (Prostate Cancer) (Wave 3) (US):

  • Satisfaction with Xofigo: The majority of surveyed medical oncologists who have prescribed Xofigo for docetaxel-naive and docetaxel-pretreated symptomatic mCRPC indicated a moderate to high level of satisfaction with the agent.
  • Advantages over current therapies: Xofigo's efficacy data, bone-targeted mechanism of action, limited treatment duration and safety profile are among its top perceived advantages over other currently available therapies, according to our survey results.
  • Prescribing patterns: A majority of surveyed medical oncologists indicated that they would most likely prescribe Xofigo to symptomatic mCRPC patients who had been pretreated with docetaxel and Zytiga. Nevertheless, over a third of respondents stated that they would most likely prescribe Xofigo to their docetaxel-naive mCRPC patients with symptomatic bone metastases and who are unwilling to receive chemotherapy.
  • Combination approaches: More than one-third of Xofigo prescribers indicated that they would prescribe Xofigo in combination with currently available agents, most likely Zytiga or Lupron/Eligard; however, a variety of other current therapies were also cited by these respondents.

Comments from Decision Resources Group Analyst Jennifer Bamford:

  • "Lack of familiarity, cost and the need to administer Xofigo at a specialist nuclear medicine facility are the standout constraints on Xofigo prescribing in symptomatic mCRPC, according to surveyed oncologists."
  • "Only a third of respondents reported no contact with any Xofigo sales representative at one year post-launch, compared with the majority of respondents in prior waves of research. Respondents indicated a high satisfaction with Xofigo sales representatives' performance, including their ability to address questions regarding product logistics."

About Decision Resources Group
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Decision Resources Group
Christopher Comfort

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