Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that 70.7 percent of newly diagnosed Alzheimer's disease patients do not receive treatment within a year of being diagnosed. The reasons for this are due to their denial, preference for no drug therapy, concerns about cost or the side-effect and safety risks associated with drug treatment. The new report entitled Treatment Algorithms in Alzheimer's Disease finds that while surveyed neurologists primarily attribute their decision not to prescribe treatment for newly diagnosed Alzheimer's disease patients to patient prerogatives, surveyed primary care physicians (PCPs) also cite presence of mild disease as a factor to delay drug treatment.
The report also finds that surveyed neurologists and PCPs both keenly anticipate the integration of disease-modifying therapies into Alzheimer's disease treatment; 72 percent of surveyed neurologists and 63 percent of surveyed PCPs report that they are "very likely" or "likely" to prescribe disease-modifying therapies first line upon their launch. However, uptake of a given disease-modifying therapy will be strongly modulated by its safety profile, as an agent with a risk for more severe side effects is likely to be prescribed primarily by neurologists.
"Surveyed PCPs' enthusiasm exists despite the fact that only eight percent of them are aware of any one of the potential disease-modifiers, such as Elan/Wyeth's bapineuzumab, that are expected to launch by 2012," said Madhuri Borde, Ph.D., analyst at Decision Resources. "In contrast, 45 percent of surveyed neurologists know of bapineuzumab, and 65 percent of this group believes that they will prescribe the drug if it is approved."
About Treatment Algorithm Insight Series
Decision Resources combines in-depth primary research with the most extensive claims-based longitudinal patient-level data from IMS Lifelink: Health Plans Claims database to provide exceptional insight into physicians' prescribing trends and the factors that drive therapy product choice, from diagnosis through multiple courses of treatment, for a specific disease.
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