• Amyloidosis a group of rare diseases caused by protein misfolding, which leads to extracellular tissue deposition of misfolded and aggregated autologous proteins as β-pleated sheet fibrils. Amyloid light-chain (AL) amyloidosis or primary systemic amyloidosis is characterized by clonal plasma cell proliferation and dyscrasia, leading to multi-organ dysfunction.
  • Given the lack of global epidemiology data for this condition, we estimated the diagnosed incidence and 20-year prevalence of AL amyloidosis in 2018 in 31 European countries (Eu) , the United States, Canada, Brazil, Japan, South Korea, Taiwan and Russia.
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